Effects of maglev-spectrum magnetic field exposure on CEM T-lymphoblastoid human cell growth and differentiation

摘要

Exposure to magnetic fields similar to those produced by maglev vehicles (combined ac and dc components) was studied for the ability to alter cell growth and chemically induced cellular differentiation processes in cultured human CEM Tlymphoblastoid leukemia cells. A series of continuous and intermittent magnetic field (MF) exposures for varying lengths of time were tested at intensities up to 7-fold greater than that produced by the German TR07 maglev vehicle. Phorbol 12-myristate 13-acetate or mycophenolic acid were used to induce cell differentiation. Changes in cell number, morphology, and fluorescence expression of antigenic markers of differentiation were monitored. The results indicated that maglev-spectrum magnetic field exposures up to 2 gauss had little effect on culture growth or chemically induced cellular differentiation when exposed to maglev-spectrum magnetic fields compared to chemically treated but MF-unexposed controls.