Ultrashort Laser Pulse Effects in Ocular and Related Media: Laser-Induced ShockWave Propagation and Retinal Damage

摘要

The overall objective of this project was to study the role of mechanical effectsin producing retinal injury as part of a larger Air Force program on ultrashort laser pulse ocular injury. Laser-induced stress transients were generated by the ablation F of a polyimide target by an excimer laser in order to study damage due only to waves, excluding confounding factors such as cavitation. The model for ocular injury consisted of retinal pigment epithelium (RPE) cells in vitro. The response of RPE cells to compressive waves has been determined using a dye