Characterization of Chiral Host-Guest Complexation in Fast Atom Bombardment MassSpectrometry

摘要

A new method has been developed for the characterization of complexion betweenhost and guest molecules. Adduct formation between chiral crown ethers 1 and 2 and enantiomeric ammonium ions 4 and 5 was examined. The reference compound 3 (achiral host) was chosen to be similar in structure to the chiral crown ethers for quantitative measurements. Our approach is based on a formalism assuming an