Methodology To Determine Homology and Clustering as Applied To Intronic Regionsof Regulatory Cancer Genes and Non-Regulatory Genes

摘要

This thesis considers the problem of statistically evaluating the closeness ofmultiple genes based on their DNA intronic regions. The purpose of intronic regions in a gene is unknown. Recent research suggests that, in cancer related genes, intronic regions may play a role in regulating disease susceptibility. To investigate whether the intronic features of cancer related genes differ from non-