Effects of Combined Caffeine and Ephedrine Ingested with a Liquid Meal onSubsequent Exercise and Performance

摘要

DCIEM has been investigating the effects of ingesting various drugs to determinetheir effect on physical performance. Two such drugs, Caffeine (C) and ephedrine (F) ingested in combination have been shown to enhance physical performance. However, in some subjects, the combination has caused nausea and vomiting during high intensity exercise. This study evaluated the effects of ingesting a standardized liquid meal, i.e., a can of ENSURE PLUS (TM), after drug ingestion and one hour before exercise, to see if the incidence of nausea could be reduced. The results indicated that in those subjects that had ingested the meal, it did not alleviate the problem of nausea, and it further attenuated the effect of the drug on performance. This response may have been a result of a number of factors, i.e., unfamiliarity of meal, closeness of meal ingestion to time of exercise, and length of fasting.