Rapid 4D MRI of Gad-DTPA Enhancement for Breast Lesion Characterization

摘要

The objectives of this project are refinement and implementation of new methodsdesigned to defeat the tradeoff between spatial resolution, temporal resolution and tissue coverage in dynamic gadolinium-enhanced MR mammography. The approach involves specialized software for data acquisition and reconstruction that allows dynamic scans of 32 sections through both breasts acquired at 10-13 second temporal resolution. Additional post-processing further improves temporal resolution to 5-6 seconds, and reduces motion artifacts for improved quantitation via in numerical fitting of temporal enhancement features of lesions. Objectives related to development of data acquisition and processing tools have been completed.