Role of CCAAT/Enhancer Binding Proteins in Mammary Tumor Promotion

摘要

This proposal investigated the influence of diet on CCAAT/Enhancer bindingproteins (C/EBPs) in mammary tumors and normal mouse tissue. Body weights of mice fed calorically restricted diets were lower than ad libitum fed mice. Body weights of mice fed high fat diets were greater than mice fed equicaloric low fat diets, suggesting that fat may be a more efficient source of dietary energy than carbohydrate. Diets did not alter mammary tumor incidence.