Post-Doctoral Training: Case-Control Analysis of Breast Cancer

摘要

This grant funded postdoctoral training for Dr. Cook's analyses investigating risk factors for breast cancer. Briefly, we found a small elevation in breast cancer risk associated with any use of hair coloring, although exclusive use of one of the four types of hair coloring application was not associated with elevated risks among reproductive-age women. Elevations in risk were not restricted to one type of hair coloring application (for example rinses or frosting) in combination with the other types. Hair spray use was not associated with an elevation in risk. Another analysis suggested that among multiparous women of the same age, parity, and age at first term birth, there was no increased risk of breast cancer for those who had their last term pregnancy late in their reproductive life compared to women who had their last term pregnancy earlier. Our results also suggested no consistent pattern of an elevated risk for breast cancer for several years following a term birth for women who have another pregnancy compared to women of the same age who do not have an additional pregnancy. Results concerning the relation between occupation and breast cancer risk in young women are pending review and approval by other investigators.