Childbearing and Survival After Breast Cancer

摘要

This project obtained data from three population-based cancer registries in the Seattle, Detroit, and Los Angeles areas to compare relative survival of women with and without births among those with breast cancer. All women less than 45 years of age diagnosed with invasive breast cancer were identified in each of the three study regions. Their records were linked with birth certificates from each state to identify those (3%) with a live birth after their initial diagnosis with breast cancer. Comparison subjects were identified from among young women with breast cancer in each region without subsequent births, matched on age and stage of disease at diagnosis, diagnosis year, race, and presence of multiple primary tumor. Date of last follow-up and vital status have been updated and 75% of all study subjects who were known to be alive have been followed for at least four years. Relative survival is compared among women with and without births subsequent to diagnosis.