Acute and Four-Week Inhalation Toxicity Study in Rats Exposed to Pyrotechnically Disseminated Black Smoke (PVA).

摘要

This study was conducted to evaluate the acute and repeated-dose toxicity of pyrotechnically disseminated black smoke (PVA) when administered by inhalation to male and female rats. Toxicity data in a mammalian system needed to be generated to assess acute and repeated-dose inhalation toxicity health hazards associated with the material to assure its safety before use by military personnel and to determine an occupational exposure level for workers.