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Research Area 14.3 Microbiology and Biodegradation: Development of RNA-based Vectors for in vivo Delivery of siRNAs.

机译：研究领域14.3微生物学和生物降解：用于体内递送siRNa的基于RNa的载体的开发。

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The purpose of this grant was to develop RNA vectors capable of delivering functional RNAi.

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作者
TenOever, B.;
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年度 2014
页码 1-20
总页数 20
原文格式 PDF
正文语种 eng
中图分类工业技术;
关键词
BIODEGRADATION; DISEASE VECTORS; MICROBIOLOGY; RIBONUCLEIC ACIDS; DELIVERY; IN VIVO ANALYSIS; RNA(RIBONUCLEIC ACIDS); RNAI(RNA INTERFERENCE); PE611102;

机译：生物降解;疾病向量;微生物学;核糖核酸;递送;体内分析; RNa（核糖核酸）; RNaI（RNa干扰）; pE611102;

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专利

1. Mechanisms and optimization of in vivo delivery of lipophilic siRNAs. [J] . Wolfrum C, Shi S, Jayaprakash KN, Nature biotechnology . 2007,第10期

机译：亲脂性siRNA体内递送的机制和优化。
2. Antigen-presenting cell-targeted lentiviral vectors do not support the development of productive T-cell effector responses: implications for in vivo targeted vaccine delivery [J] . Goyvaerts C., De Vlaeminck Y., Escors D., Gene therapy . 2017,第6期

机译：抗原呈递细胞靶向的慢病毒载体不支持生产T细胞效应器反应的发展：在体内靶向疫苗递送的影响
3. Inhibition of simian immunodeficiency virus by foamy virus vectors expressing siRNAs. [J] . Park J, Nadeau P, Zucali JR, Virology . 2005,第2期

机译：表达siRNA的泡沫病毒载体对猿猴免疫缺陷病毒的抑制作用。
4. Invivo-invitro Biodegradation and Tissue Compatibility of Novel Biomaterial used as Ciprofloxacin Implant for Drug Delivery System [C] . M. S. Charde, R. M. Charde, S. V. Fulzele, Controlled Release Society Annual Meeting and Exposition . 2007

机译：新型环丙沙星植入物用于药物递送系统的新型生物材料的体内-体外生物降解和组织相容性
5. Understanding barriers to in vivo gene delivery and developing nonviral vectors for more efficient gene delivery. [D] . Burke, Rob S. 2009

机译：了解体内基因传递的障碍并开发非病毒载体以实现更有效的基因传递。
6. Multiple Immediate-Early Gene-Deficient Herpes Simplex Virus Vectors Allowing Efficient Gene Delivery to Neurons in Culture and Widespread Gene Delivery to the Central Nervous System In Vivo [O] . Caroline E. Lilley, Filitsa Groutsi, ZiQun Han, 2001

机译：多个立即早期基因不足的单纯疱疹病毒载体可以有效地将基因传递给培养中的神经元并将广泛的基因传递给体内中枢神经系统
7. Development of targeted gene delivery vectors to assess cardiac overexpresion of ACE2 in vivo [O] . Shirley Rachel 2008

机译：开发靶向基因递送载体以评估体内aCE2的心脏过度表达

Research Area 14.3 Microbiology and Biodegradation: Development of RNA-based Vectors for in vivo Delivery of siRNAs.

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