Effects on Ocular Tissue of Multiple Laser Pulses and of Single Ultrashort Pulses of Varying Wavelength.

摘要

In order to evaluate laser safety standards, Dr. Toth examined fluorescein angiograms (in some cases OCT) and fixed tissue sections and aided in defining exposure limits for pulse widths less than one nanosecond. In our initial short pulse study, we were concerned with the restriction to a single wavelength. To verify that the tissue effects were due to the pulse structure, we obtained data outside a single wavelength. We obtained from information from -530-nm and -1060nm wavelengths to compare to data obtained from previous studies of visible laser picosecond and femtosecond pulses. The type of lesions created with 530 and 1060-1064nm wavelengths were similar to the lesions created in the earlier 580-nm wavelength studies. This supported the theory that laser induced breakdown is one of the primary damage mechanisms for ultrashort laser pulses. Data from our studies was used by the American National Standard Institute in publications ANSI Z136.1, 'Safe Use of Lasers' (updated 2000) and ANSI Z136.3, 'Safe Use of Lasers in Health Care Facilities' (1996).