Experimental Setup for the Quantification of the Cardiopulmonary Responses to Different Artificial Respiratory Loads.

摘要

In order to investigate the effect induced on respiratory and cardiocirculatory activity by mechanical dysfunction in the respiratory system, devices were designed and constructed for increasing both resistive and elastic respiratory load, thus simulating obstructive and restrictive pathologies, respectively. The resistive load was obtained as a duct, with a resistive core, having linear characteristic; elastic load was obtained by imposing the respiration from a closed volume. The elastic load too had linear characteristics. The artificial load were calibrated for producing a total load about three times the normal intrinsic load and were applied to a group of normal subjects. A set of signals from the respiratory and cardiocirculatory system were recorded and analyzed through proper algorithms for obtaining quantitative parameter both in time and frequency domain.