Glucosim: A Simulator for Education on the Dynamics of Diabetes Mellitus.

摘要

Glucose-insulin interactions in healthy and insulin-dependent diabetic humans are simulated using an overall and a detailed model based on pharmacoki-netic diagrams of insulin and glucose. Both models are capable of predicting blood glucose and insulin levels, total glucose uptake and renal glucose excretion. The simulator is integrated with a graphical user interface to provide a user-friendly environment for performing virtual experiments with various characteristics, diet and exercise conditions.