Predicting Behavioral Suites From Genetic Profiles: Variation in Mating, Aggression & Exploration in Pouched Rats.

摘要

This project aimed to investigate individual variation in genes and behavior. Behavioral variation has been characterized by some in terms of Proactive and Reactive behavioral repertories, or personalities . This project examined the behavior of African giant pouched rats (Cricetomys ansorgei, formerly C. gambianus) to understand their mating behavior and to determine the extent to which they demonstrate proactive and reactive personalities. The First Objective used field and lab methods to describe the basic biology of this species. The Second Objective was to assess behavior across a series of tests designed to determine the aggression, exploratory behavior, learning & memory, anxiety, and stress-coping responses of individuals to identify personality types. The Third Objective was to identify genetic patterns associated with animals from the upper and lower quartiles tested in the second objective, in an effort to identify genetic signatures that predict behavioral predisposition for learning and exploration under different circumstances. Despite good progress, much of the project remains incomplete due to delays from importing animals and because the PI changed institutions. As a result, the state of the project is only partially complete. The project will continue under a new award (W911NF-14-1-0376) aimed at completing the aims outlined in this original project.