Development and Translation of Hybrid Optoacoustic/Ultrasonic Tomography for Early Breast Cancer Detection.

摘要

The broad objective of the proposed research is to develop an optimized system design and associated image reconstruction algorithms for a hybrid three-dimensional (3D) breast imaging system that combines OAT and UST. Significant progress has been made during last year in accomplishing the specific tasks for this project. In the past year, I (i) developed time-offlight extraction algorithms to perform USCT, (ii) developing image reconstruction algorithms for USCT, (iii) developed iterative image reconstruction OAT algorithms (iv) developed accelerated OAT algorithm to enable 3D image reconstruction for breast imaging, (v) evaluated and validated algorithms by computer simulation studies and experimental phantom studies.