Rapid PCR Assays That Specifically Identify Anthrax and Anthrax Surrogate Chromosomal Signatures

摘要

The genetic variation among a set of 175 full-length sspE DNA sequences obtained from representative members of the B. anthracis clade have been examined. Thirty-six sspE genotypes and seventeen protein phylotypes were identified among the B. cereus, B. thuringiensis, B. anthracis and B. mycoides strains analyzed. The most extensive genetic diversity was seen in B. thuringiensis strains representing 78 serovar classes. Computational analysis of the sspE DNA sequence data sets suggests that the B. anthracis dade is more phylogenetically complex than has been inferred by traditional taxonomic methods.