Prediction of Pathologic Fracture Risk in Activities of Daily Living and Rehabilitation of Patients With Metastatic Breast Carcinoma of the Pelvis and Femur

摘要

The purpose of the project was to develop a computer model of the pelvis and proximal femur which could be used to predict pathologic fracture risk and study the effects of pelvic and proximal femoral metastatic bone lesions on the care and management of breast cancer patients. The scope of the research was to construct graphical and quantitative models of the pelvis and proximal femur on a computer workstations including Finite Element Method and Discrete Element Method to study the stress and strain in the pelvis and proximal femur and pressure distribution of the hip joint in the patient with metastatic bone lesions of the breast cancer in the pelvis and proximal femur with interactive capability. This project resulted in the development of a computer model of the hip joint which can be used to predict the pathologic fracture risk and study the effects of metastatic bone lesions on the hip joint. The computer model is user-friendly and interactive, and the critical areas for pathologic fracture during various activities can be demonstrated in three- dimensional graphics and animations. This computer model will aid in planning of non-operative or operative management, rehabilitation regimens, nursing programs, and patient education.