Biological Activities of Fusarochromanone: a Potent Anti-cancer Agent.

摘要

Fusarochromanone (FC101) is a small molecule fungal metabolite with a host of interesting biological functions, including very potent anti-angiogenic and direct anti-cancer activity. Our data presented here indicates that FC101 is an excellent lead candidate for small molecule anti cancer agent that simultaneously affects angiogenesis signaling, cancer signal transduction, and apoptosis. further understanding of the underlying FC101's molecular mechanism may lead to the design of novel targeted and selective therapeutics, both of which are pursued targets in cancer drug discovery.