Electromagnetic-Optical Coherence Tomography Guidance of Transbronchial Solitary Pulmonary Nodule Biopsy.

摘要

We present a novel high-resolution multimodality imaging platform utilizing CT and electromagnetic (EM) navigation for spatial guidance to targeted lung nodules, and OCT for microscopic volumetric imaging. The OCT optic fiber probe and EM sensor were incorporated into a single flexible catheter. The catheter was designed to be compatible with a custom peripheral transbronchial aspiration needle to enable both imaging and specimen collection. The EM sensor guides the catheter and biopsy needle to the spatial location of the pulmonary nodules and OCT images are obtained to microscopically assess the tissue.