Genome of Bacillus cereus 14579: A Local Analysis

摘要

Due to its close genetic and biochemical identity to Bacillus anthracis, B. cereus can be used as a lower risk pathogen in order to model anthrax biochemistry. The recent sequencing of the B. cereus 14579 genome has assisted in this process. This report presents the results of a locally performed analysis and annotation of the B. cereus 14579 genome. 4885 putative open reading frames were detected, with 2946 of these identified through homology searching. These identified gene products were then used for metabolic reconstruction of the organism, with an emphasis on potential enzymes involved in regenerating methionine from methylthioadenosine. The present results demonstrate the ease and utility of local genome analysis as a tool for assisting in research studies at DRDC Suffield.