Electrical Properties of Solid-State Nanopore Sensors

摘要

This final report documents support from ONR in developing a solid state single molecule sensor. The sensor uses a voltage biased nanopore in an insulating membrane that separates two pools of conducting salt water. The biased nanopore attracts and translocates charged biopolymers like DNA. The ionic current that flows through the pore is sensitive to the presence of single molecules and can be used to measure their passage. In this work we demonstrate the process using solid state pores for the first time.