General Purpose Analysis System Based on a Programmable Fluid Processor

摘要

The goal of this project was to develop a complete system for droplet chemistry and biowarfare detection applications based on a programmable dielectrophoretic array concept. In this final reporting period design and testing of the 4th and 5th generation SOI chip was completed. A silicon and glass solid-state microfluidics system was designed at M. D. Anderson and successfully fabricated and integrated with the SOI chip at Applied MEMS. Simultaneously, cost savings in foundry work permitted an additional iteration in the final design of the integrated electrode array. Identifying and implementing the new microfluidics technology and developing the technique to bond it to the revised SOI chip imposed a delay of some 11 months on the project completion which will was used to integrate the new microfluidics with the revised chip. With the accomplishment of these steps, all of the major aims of the project have been successfully completed. Thus, a programmable fluidic processor platform capable of on-the-fly adaptation to multiple testing challenges and based on dielectrophoretic manipulation of microdroplets has been successfully developed and demonstrated. A complete software solution for programming the system has also been provided. Finally, this new technology has been licensed for commercial development.