Needle-Free Inhalable Vaccine and Antibiotic Powder Aerosols

摘要

Multiple constituents can be incorporated in three fluids in a low volume cross to make heterogenous and homogenous nanoparticles and microparticles. 'Pharmaceuticals, proteins, antibodies, and vaccines can be stabilized, dried, and micronized by a newly patented process, CAN-BD.' A SF nebulization, desolvation and coating method (CANBD) has been developed that can manufacture dry powders and coatings of many materials. 'Coating and drying requires only seconds. 'Water and many organic solvents yield nanoparticles and microparticles with unique compositions and properties.' Fluid ratios, pressures, and solute concentrations determine particle size.