Glyco-Immune Diagnostic Signatures and Therapeutic Targets of Mesothelioma.

摘要

The focus of this grant is to investigate immunoprofiles for serum antibodies to aberrant glycans in human and animal models of mesothelioma. This is accomplished using a one of a kind printed glycan array which is at NYU School of Medicine (NYUSoM). It is hoped that these experiments will allow us to diagnose and prognosticate mesothelioma more accurately in the future. We have been severely limited by our ability to start the human mesothelioma glycoprofiles as well as the animal profiles due to delivery and set up times for our one of a kind glycomics laboratory at NYUSoM. We summarize the situation in the progress report with the good news that we will be moving onwards in June with these studies.