Pharmacological and Nonpharmacological Methods of Treatment for Fragile X Syndrome

摘要

Fragile X (FX) syndrome causes behavioral disturbances such as labile mood, anxiety, hyperactivity, and aberrant behavioral responses to stress. Affected males may suffer from learning disabilities, attention deficit disorders, mental retardation, or autism spectrum disorders. We seek to address the most effective methods of treatment (pharmacological and behavioral) for the symptoms and behavioral problems associated with FX syndrome. During the past year, we have established a comprehensive FX syndrome clinic and we continue to refine our treatment protocol. Collaborative relationships have been established with genetics, speech/language, psychiatry, and dental so that families can obtain these services from specific professionals with an interest in FX syndrome. School liaison services for school aged youth with FX syndrome have been established. Community education programs, in the form of a website, a parent advisory group, and newsletters have been established. We continue to refine our database to track the frequency of the disease and specific symptoms with the goal of guiding future treatment through evidence based medicine.