Randomized Trial of Neuroprotective Effects of Erythropoietin in Patients Receiving Adjuvant Chemotherapy for Breast Cancer: Position Emission Tomography and NE

摘要

Adjuvant treatment with Adriamycin and cyclophosphamide (AC) clearly prolongs the overall survival in women with breast cancer. Cognitive deficits (e.g. problems with memory and concentration) are common during and after adjuvant breast cancer chemotherapy, but the pathophysiology of cognitive phenomens is unknown. The goal of this project is to study the pathophysiology of cognitive dysfunction in patients receiving adjuvant treatment using Positron Emission Tomography (PET) scan.