Modifiable Risk Factors for Lymphedema in Breast Cancer Survivors; Annual rept. 1 Oct 2005-30 Sep 2006

摘要

Lymphedema of the arm is a consequence of breast cancer treatment that can result in substantial functional impairment and distress. In this study, women diagnosed with a first primary invasive breast cancer and treated with axillary lymph node dissection will be identified through a population- based cancer registry. The incidence and timing of arm edema will be assessed using physical measures (arm volume) and self-reported arm symptoms. In total, 443 women enrolled in the study; to date, 423, 404 and 292 women have completed their second, third, and fourth interview and measurements. A preliminary analysis, based on enrollment data, was presented at the DOD Era of Hope meeting in June, 2005. We found that increasing body mass was positively associated with the occurrence of arm swelling identified by self-report or by measured arm volume. Future analyses will assess changes in arm volume over time and relationships of arm swelling with treatment and lifestyle factors.