Bioaerosol Challenges to Antimicrobial Surface Treatments: Enhanced Efficacy Against MS2 Coli Phage of Air Filter Media Coated With Polystyrene-4- Methyltrimethylammonium Triiodide

摘要

Two samples each of two commercial (COTS) soft respiratory protection (SRP) masks and seven SRP masks augmented with a quaternary ammonium derivative of polystyrene as the triiodide salt were sealed to an adapter and challenged for 6 hours with an aerosol containing '10(8) plaque-forming units (PFUs) of MS2 coli phage. Compared to a positive control (open path), average % reduction in PFUs for the first and second COTS and the iodinated SRP masks was 98.18%, 99.55% and 99.9945%, respectively. The two-log enhancement in removal efficiency is attributed to the available iodine's killing '99% of penetrating coli phage particles. In a swatch test, 47-cm2 discs of the iodinated medium cut from a mask achieved 99.9999% average % reduction in PFUs.