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Gene Therapy to Extend Lifespan of Tsc1 Conditional Brain Knockouts.

机译：基因疗法延长Tsc1条件性脑剔除的寿命。

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作者
Breakefield, X. O.;
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年度 2015
页码 1-15
总页数 15
原文格式 PDF
正文语种 eng
中图分类
关键词
Genes; Gene therapy; Brain; Genetic diseases; Neurons; Tuberous sclerosis complex (tsc); Adeno-associated virus (aav);

机译：基因;基因治疗;脑;遗传疾病;神经元;结节性硬化症复合体（tsc）;腺相关病毒（aav）;

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1. Intrathecal gene therapy significantly extends lifespan of the Twitcher mouse and the Krabbe dog models [J] . Hordeaux J., Jian J., Jahan T., Human gene therapy . 2019,第11期

机译：鞘内基因治疗显着延伸了抽搐鼠标和Krabbe狗模型的寿命
2. Intrathecal and intravenous combination gene therapy in the mouse model of infantile neuronal ceroid lipofuscinosis extends lifespan and improves behavioral outcomes in moderately affected mice [J] . Gray Steven J., Rozenberg Alejandra, Lykken Erik, Molecular genetics and metabolism . 2019,第2期

机译：在婴儿神经元曲线型唇裂病变的小鼠模型中的鞘内和静脉内联合基因治疗延伸了寿命并改善了中等受影响的小鼠的行为结果
3. Combination dosing of CLN1 gene therapy extends lifespan in a mouse model of infantile neuronal ceroid lipofuscinosis [J] . Rozenberg Alejandra J., Lykken Erik, Spratt Kaye, Molecular genetics and metabolism . 2018,第2期

机译：CLN1基因治疗的组合给药在婴儿神经元曲线唇裂病毒态病变的小鼠模型中延伸了寿命
4. Braincubator: An incubation system to extend brain slice lifespan for use in neurophysiology [C] . Breen Paul P., Buskila Yossi Annual International Conference of the IEEE Engineering in Medicine and Biology Society . 2014

机译：Braincubator：用于延长脑片寿命的孵化系统，用于神经生理学
5. Analysis of the role of two autophagy pathway related genes, Becn1 and Tsc1, in murine mammary gland development and differentiation. [D] . Hale, Amber N. 2014

机译：分析两个自噬途径相关基因Becn1和Tsc1在鼠乳腺发育和分化中的作用。
6. Alpha 1 Antitrypsin Gene Therapy Extends the Lifespan of Lupus-Prone Mice [O] . Ahmed Samir Elshikha, Ye Yuan, Yuanqing Lu, 2018

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7. Chronic monotherapy with extended release metoprolol succinate attenuates mRNA gene expression of brain and atrial natriuretic peptides in left ventricular myocardium of dogs with heart failure [O] . Rastogi Sharad, Gupta Ramesh C., Mishra Sudhish, 2003

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Gene Therapy to Extend Lifespan of Tsc1 Conditional Brain Knockouts.

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