High Resolution X-Ray Phase Contrast Imaging with Acoustic Tissue- Selective Contrast Enhancement

摘要

We show that laser-driven thermal modification can be used to selectively enhance regions of a flowing carbon suspension. The preliminary proof-of-principle experiments illustrate the ability to measure thermal modifications in a time-resolved manner utilizing x-ray phase-contrast imaging paving the way for implementation in a biological model. Additional results of biological tissue sample measurements are presented. X-ray phase-contrast images of murine hepatic and pulmonary samples reveal fine structure usually visible only by utilizing histological or microscopy techniques. The method holds promise for future applications to study murine models of pulmonary and hepatic disease.