Role of Polyamine Oxidase (PAOh1/SMO) in Human Breast Cancer

机译：多胺氧化酶（paOh1 / smO）在人乳腺癌中的作用

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This report provides an update on the study of the role of polyamine oxidase(PAOh1/SMO, spermine oxidase) in drug response of human breast cancer. Thecytotoxic effects of two novel polyamine analogue compounds, CGC-11144 and CGC- 11047 were evaluated in the human breast cancer cell lines MDA-MB-231, Hs578t,MCF-7, 468, and T47D. Additionally, the hypothesis that induction of spermine oxidase by pro-inflammatory agents plays a role in carcinogenesis was evaluated using a model system of exposure of MCF-10a human breast epithelial cells tocigarette smoke extract (CSE).

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作者
Goodwin, A. C. ; Richards, T. A.;
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年度 2007
页码 1-11
总页数 11
原文格式 PDF
正文语种 eng
中图分类工业技术;
关键词
Polymers; Enzymes; Response(Biology); Growth(Physiology); Cells(Biology); Breast cancer; Neoplasms; Inhibition; Induction systems; Mammary glands;

机译：聚合物;酶;反应（生物学）;生长（生理学）;细胞（生物学）;乳腺癌;肿瘤;抑制;诱导系统;乳腺;

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1. The role of the polyamine catabolic enzymes SSAT and SMO in the synergistic effects of standard chemotherapeutic agents with a polyamine analogue in human breast cancer cell lines. [J] . Pledgie Tracy A, Billam M, Hacker A, Cancer chemotherapy and pharmacology. . 2010,第6期

机译：多胺分解代谢酶SSAT和SMO在标准化学治疗剂与多胺类似物在人乳腺癌细胞系中的协同作用中的作用。
2. The role of the polyamine catabolic enzymes SSAT and SMO in the synergistic effects of standard chemotherapeutic agents with a polyamine analogue in human breast cancer cell lines [J] . Allison Pledgie-Tracy, Madhavi Billam, Amy Hacker, Cancer Chemotherapy and Pharmacology . 2010,第6期

机译：多胺分解代谢酶SSAT和SMO在人乳腺癌细胞系中标准化疗剂与多胺类似物的协同作用中的作用
3. The role of the polyamine catabolic enzymes SSAT and SMO in the synergistic effects of standard chemotherapeutic agents with a polyamine analogue in human breast cancer cell lines [J] . Allison Pledgie-Tracy, Madhavi Billam, Amy Hacker, Cancer Chemotherapy and Pharmacology . 2009,第6期

机译：多胺分解代谢酶SSAT和SMO在人乳腺癌细胞系中标准化疗剂与多胺类似物的协同作用中的作用
4. Measurement of Human Breast Tumor Cell-Secreted shNDPK-B in a Murine Breast Cancer Model Suggests its Role in Metastatic Progression [C] . Nucharee Yokdang, Noah D. Buxton and lain L. 0. Buxton* Western Pharmacology Society . 2009

机译：在鼠乳腺癌模型中的人乳腺肿瘤细胞分泌的ShNDPK-B的测量表明其在转移性进展中的作用
5. The role of the polyamine catabolic enzymes spermine oxidase (SMO) and spermidine/spermine N1-acetyltransferase (SSAT) in the drug response of human non-small cell lung cancer cells [D] . Fleischer, Jennifer Greenlaw 2008

机译：多胺分解代谢酶精胺氧化酶（SMO）和亚精胺/精胺N1-乙酰基转移酶（SSAT）在人非小细胞肺癌细胞药物反应中的作用
6. The role of the polyamine catabolic enzymes SSAT and SMO in the synergistic effects of standard chemotherapeutic agents with a polyamine analogue in human breast cancer cell lines [O] . Allison Pledgie-Tracy, Madhavi Billam, Amy Hacker, -1

机译：多胺分解代谢酶SSAT和SMO在人乳腺癌细胞系中具有多胺类似物的标准化学治疗剂的协同作用中的作用
7. The role of the polyamine catabolic enzymes SSAT and SMO in the synergistic effects of standard chemotherapeutic agents with a polyamine analogue in human breast cancer cell lines [O] . Allison Pledgie-Tracy, Madhavi Billam, Amy Hacker, 2009

机译：多胺分解代谢酶SSAT和SMO在人乳腺癌细胞系中具有多胺类似物的标准化学治疗剂的协同作用中的作用

Role of Polyamine Oxidase (PAOh1/SMO) in Human Breast Cancer

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