Quarterly Performance/Technical Reports: HLA Typing for Bone Marrow Transplantation, and Development of Medical Technology for Contingency Response to Marrow Toxic Agents

摘要

N00014-05-1-0310: Task 1: Evaluate optimal short term storage parameters for stimulated and unstimulated leukapheresis (donor lymphocytes) and bone marrow products, including the type of storage media and the cell concentration, in addition to temperature and duration of storage before processing or infusion. Task 2: The NMDP has developed an algorithm that 'predicts' high resolution HLA typing results on donor samples that exist in the Registry with only low or intermediate results reported. N00014-05-1-0859 and N00014-06-1-0704: Task 1: Contingency preparedness. Task 2: Rapid identification of matched donors. Task 3: Immunogenetic studies. Task 4: Clinical research in transplantation.