Closed-Loop Noninvasive Ultrasound Glucose Sensing and Insulin Delivery

摘要

Numerous studies have shown that ultrasound can successfully be used for noninvasive blood glucose monitoring and transdermal insulin delivery. To facilitate the ability of a diabetic patient to avoid repeated needle sticks to monitor blood glucose level and painful daily injections of insulin, this basic research proposal will study the feasibility of safe and portable ultrasonic system to do both. Specifically using the low profile and light weight 'cymbal' transducer, a potentially portable ultrasound array of will be designed. Moreover the feasibility of a 'smart' diabetes management system will be developed to control both the glucose monitoring and insulin delivery system. The report herein describes the year one progress for this award and there are no deviations from the original research plan and this research is progressing on schedule.