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Effect of Aluminum Hydroxide Adjuvant and Formaldehyde in the Formulation of rPA Anthrax Vaccine

机译：氢氧化铝辅助剂和甲醛在rpa炭疽疫苗配方中的作用

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The serological response and efficacy of Bacillus anthracis recombinant protective antigen (rPA) vaccines formulated with aluminum hydroxide adjuvant, either with or without formaldehyde, were evaluated in rabbits. Rabbits that had been injected with a single dose of 25mug of rPA adsorbed to 500mug of aluminum in aluminum hydroxide gel (Alhydrogel) had a significantly higher quantitative anti-rPA IgG ELISA titers.

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作者
Little, S. F. ; Ivins, B. E. ; Webster, W. M. ; Norris, S. L. ; Andrews, G. P.;
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年度 2007
页码 1-9
总页数 9
原文格式 PDF
正文语种 eng
中图分类工业技术;
关键词
Anthrax; Vaccines; Reprints; Enzymes; Aluminum; Formaldehyde; Laboratory animals; Bacillus anthracis; Rabbits; Hydroxides; Serology; Antibodies; Response(Biology);

机译：炭疽;疫苗;重印;酶;铝;甲醛;实验室动物;炭疽杆菌;兔;氢氧化物;血清学;抗体;反应（生物学）;

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1. Effect of aluminum hydroxide adjuvant and formaldehyde in the formulation of rPA anthrax vaccine [J] . Little SF, Ivins BE, Webster WM, Vaccine . 2007,第15期

机译：氢氧化铝佐剂和甲醛在rPA炭疽疫苗配方中的作用
2. Glassy-State Stabilization of a Dominant Negative Inhibitor Anthrax Vaccine Containing Aluminum Hydroxide and Glycopyranoside Lipid A Adjuvants [J] . Hassett Kimberly J., Vance David J., Jain Nishant K., Journal of pharmaceutical sciences. . 2015,第2期

机译：含氢氧化铝和糖精苷脂质A佐剂的主要阴性抑制剂炭疽疫苗的玻璃态稳定化。
3. Structural characterization of a protein adsorbed on aluminum hydroxide adjuvant in vaccine formulation [J] . Linda Cerofolini, Stefano Giuntini, Enrico Ravera, NPJ vaccines. . 2019,第1期

机译：吸附在氢氧化铝辅助液中丙酮铝溶液中的蛋白质的结构表征
4. NOVEL Vaccine Formulations Encapsulating Aluminum Hydroxide (Alum): Immune Response and Stability of Antigens [C] . S. HAYAVI, L .BAILLIE, D.Williamson, Proceedings of the 29th Annual Meeting of the Controlled Release Society . 2002

机译：封装氢氧化铝（明矾）的新型疫苗配方：免疫应答和抗原稳定性
5. Oil -in -water nanoemulsions as mucosal vaccine adjuvants: Characterization, mechanism, formulation, and development of a nanoemulsion-based Burkholderia cenocepacia vaccine [D] . Makidon, Paul Edward 2009

机译：水包油纳米乳剂作为粘膜疫苗佐剂：基于纳米乳剂的伯克霍尔德菌新球菌疫苗的表征，机理，配方和开发
6. Glassy-State Stabilization of a Dominant Negative Inhibitor Anthrax Vaccine Containing Aluminum Hydroxide and Glycopyranoside Lipid A Adjuvants [O] . Kimberly J. Hassett, David J. Vance, Nishant K. Jain, -1

机译：含氢氧化铝和糖精苷脂质A佐剂的主要阴性抑制剂炭疽疫苗的玻璃态稳定化。
7. Resiquimod and polyinosinic–polycytidylic acid formulation with aluminum hydroxide as an adjuvant for foot-and-mouth disease vaccine [O] . Chun-Xue Zhou, Dong Li, Ying-Li Chen, 2014

机译：氢氧化铝作为口蹄疫疫苗佐剂的雷西莫德和多肌苷-聚胞苷酸制剂

Effect of Aluminum Hydroxide Adjuvant and Formaldehyde in the Formulation of rPA Anthrax Vaccine

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