Design, Implementation, and Characterization of a Dedicated Breast Computed MammoTomography System for Enhanced Lesion Imaging; Annual summary, 1 Mar 2005-29 Feb 2008

摘要

The overall goal of this work was to design, implement, and characterize a novel dedicated mammotomography system for enhanced lesion detection. This novel system allows fully 3-D imaging of a pendant, uncompressed breast using novel 3-D complex orbit capabilities. A prototype system has been designed, developed, and extensively characterized with a number of figures of merit including SNR, dose efficiency, and contrast sensitivity. Results indicate the potential for sub dual-view dose uncompressed breast imaging. Observer studies have been performed to determine the lower limits of detectibility. Patient bed optimization has also been performed as well as system/bed positioning and tilt angles for optimal chest wall imaging and patient comfort. The outcome of this project is a fully functioning 3D dedicated breast imaging system ready for initial patient studies. In addition, the training provided by this grant has allowed the PI to continue on with further research and development of this system through SBIR and North Carolina state funding with the goal of commercialization.