Multidrug-Resistant Gram-Negative Bacterial and Carbapenem-Resistant Enterobacteriaceae Infections in the Department of the Navy: Annual Report 2013.

摘要

Gram-negative bacterial infections are a growing global public health and clinical concern. Additionally, epidemics of multidrug-resistant (MDR) gram-negative bacteria have occurred worldwide in the last couple decades, including regions where United States (US) military forces are regularly deployed. In 2013, the incidence of MDR Escherichia coli, Enterobacter, Klebsiella, and Pseudomonas aeruginosa in Department of Defense (DOD) beneficiaries seeking care in the Military Health System (MHS) increased from 2012. MDR E. coli was the organism most frequently identified with an incidence 37-40 times higher than the next most frequent organism. A pronounced gender disparity was noted for all organisms except MDR P. aeruginosa. Overall, DOD female beneficiaries were impacted much more than their male counterparts. Furthermore, MDR E. coli, MDR Enterobacter, and MDR Klebsiella cases commonly manifested as urinary tract infections (UTIs), which is consistent with historic observations. In 2013, cases of MDR P. aeruginosa more commonly manifested as respiratory infections, which is also consistent with historic observations. MDR P. aeruginosa did not display any consistent high susceptibilities at the population level.