Internet-Based Cervical Cancer Screening Program; Final rept. 15 Mar 2004-14 Dec 2007

摘要

This project explores the combination of computerized automated primary screening of cervical cytology specimens in remote sites with interpretation of device-selected images transmitted via the Internet. The project is in 3 phases: (1) hardware/software and interface development and end user training with a 200 case pilot study; (2) a 500 case prospective pilot study with hardware/software adjustment with the development of clinically applicable specimen triage and management guidelines; and (3) a 5000 case prospective clinical trial of the completed system with report and development of a training and operation manual. During this report pedod phase 2 patient accrual was completed at the Massachusetts General and Walter Reed sites. Modifications to the image acquisition and reading/reporting software have been completed. All phase 2 patients have been entered into the system and are ready for reading (which will take place by July 2008). Preliminary planning for phase 3 is near complete with IRB submissions planned for summer 2008.