Serum S-100 Beta Response to Exercise-Heat Strain Before and After Acclimation; Journal article

摘要

Exercise alone or in combination with environmental heat stress can elevate blood S-100 beta protein concentrations. However, the explanatory power of exercise with marked environmental heat stress on the appearance of S-100 beta is questionable. It is possible that the process of heat acclimation might afford additional insight. Purpose: Determine the S-100 beta response to moderate intensity exercise with heat strain before and after heat acclimation. Methods: Nine healthy male volunteers completed 10 consecutive days of heat acclimation consisting of up to 100 minutes of treadmill walking 91.56 m/s, 4% grade in the heat (45 deg C, 20% relative humidity). Changes in heart rate (HR), rectal temperature (Tre), and sweat rate (SR) were examined to determine successful acclimation. Area under the curve (AUC) for Tre > 38.5 deg C was calculated to assess cumulative hyperthermia. Blood samples were taken before and after exercise on days 1 and 10 and analyzed for serum osmolality and S-100 beta concentration. Results: All subjects displayed physiological adaptations to heat acclimation, including a significant.