Label-Free THz-Optoelectronic Sensing of Ultra-Low Concentration of Genetic Sequences: Theoretical Treatment

摘要

An engineering and mathematics research project is performed to develop the science base and simulation capability for the study, analysis and design of highly-integrated and molecular-based information processing systems. Specifically, this research investigate MQCA architectures as a potential new paradigm for information processing through the development of: (1) detailed models of the interacting molecular-level components, and (2) robust simulation algorithms that are capable of treating phenomenon associated with nonlinear dynamical complexity. Here, it is crucial to understand the interaction between the molecular devices and the substrates. To this connection, we analyze the electrostatic characteristics of the tether atoms connecting organic molecules onto silicon (100) -2 xl surfaces, which is a key factor in the design of molecular devices for information processing and biomolecular sensing. Design principles for silicon surfaces with required electrostatic functionality are presented.