Ferritin-Polymer Conjugates: Grafting Chemistry and Self-Assembly

摘要

In the MURI program on Bio-Directed Hierarchical Assembly of Multifunctional Materials we have developed routes to isolate, purify and functionalize symmetric and asymmetric bionanoparticles (viruses) in large quantities; investigated their interfacial assembly; their co-assembly with synthetic block copolymers, and developed chemistries on the assembled nanoparticles for encapsulation and delivery applications. Our theoretical studies have guided us in defining the parameters that control the assemblies at fluid interfaces, in multilayered composites.