AFSOR Bio-X: Encapsulated DNA-Based Molecular Autonomous Sensing Devices With Photonic I/O

摘要

Purpose of this program was DNA-based nanostructure detector system development and demonstration with multispectral optical readouts. The overarching goal of this research was the remote hyperspectral detection of molecular targets, with application as a combat ready, modular, general purpose target detection and signal amplification system coupled to airborne imaging systems. The specific Tasks of this project were: (1) To develop systems that amplify detection events through the use of existing biomolecular amplification methods; (2) To optimize hydrogel/aerogel encapsulation and preservation of the biomolecular detection systems to ensure robust activity upon rehydration in the field; (3) To demonstrate remote detection by such systems using hyperspectral imaging.