Molecular Profiling of Prostate Cancer Specimens Using Multicolor Quantum Dots

摘要

Each person's cancer is as unique as his or her fingerprint, which explains unpredictable responses to therapies and poses new biotechnology challenges for tumor characterization on the molecular level. For these reasons, it is of pivotal importance to develop novel molecular profiling methodologies for diagnosis, prognosis and individually tailored therapeutics of patients based on the biology of their tumors. We proposed to develop oligonucleotide tagged quantum dots and antibodies for multiplexed imaging of prostate cancer samples.