Optimization of Tomosynthesis Imaging for Improved Mass and Microcalcification Detection in the Breast

摘要

The goal of this research is to obtain systematic understandings of the effects of various physical factors that are important in breast tomosynthesis imaging and to develop techniques for effectively dealing with their effects and for reducing radiation dose. During the second year of the project we have achieved fruitful results based upon the progress made in our first year of the project. Specifically, we have further investigated the performance of the total-variation (TV) based algorithm under different data conditions and different constraint parameters. Furthermore, we have also proposed and investigated a new tomosynthesis imaging method with non-planar trajectories for yielding more data information with the same amount of imaging dose. We have also simulated the scatter in tomosynthesis breast imaging by convolving the ideal projection data with angular dependent scatter kernel.