Endobronchial Photoacoustic Microscopy for Staging of Lung Cancer.

摘要

This project is to propose an endoscopic photoacoustic imaging method for lung cancer staging. In order to obtain the image of the lymph node at different depths, the tunable liquid lens is demonstrated to evaluate the performance of tunable focusing. To achieve this goal, we work on this project based on the following aspects: 1. Characterization and optimization of the tunable acoustic lens. 2. Design and optimization of the housing of the probe. 3. Phantom experiments using the proposed probe. According to our current results, we have successfully demonstrated the prototype of the tunable endoscopic photoacoustic imaging probe and system. The lymph-node/tumor mimicking phantom and nanoparticle/dye for lymph node imaging have also been tested.