Optogenetic Activation of the Sublaterodorsal (SLD) Nucleus Induces Rapid Muscle Inhibition.

摘要

The sublaterodorsal (SLD) nucleus is hypothesized to induce muscle atonia during rapid eye movement (REM) sleep. This was tested by injecting channelrhodopsin into the SLD of 5 rats, followed by a series of behavioral tests. Results confirmed our ability to rapidly induce muscle atonia following optogenetic stimulation of the SLD, suggesting that activation of the SLD is sufficient to cause a REM atonia like state.