Design and Construction of a 1,4-Dioxane Vapor Generation System

摘要

A rodent, whole body inhalation study to characterize the biological effects of 1,4-Dioxane (dioxane) gas necessitated the development of a generation system capable of creating 6000 parts per million of dioxane in a 180 liter per minute air flow. Heat was required to counteract evaporative cooling of the dioxane while avoiding excessive heat so as not to increase temperatures in the exposure chamber. A variable alternating current transformer (Variac) was used to control two heating cords. The first warmed the glass generator body while the second heated the air passing through the generator. The temperatures used were sufficient to allow complete vaporization of the dioxane at 6000 ppm while not significantly increasing exposure chamber temperatures.