Sensory Dysfunction in Early Parkinson's Disease

摘要

This annual report presents the progress made, to date, in understanding the influences of early Parkinsons disease on all major sensory systems in the same subject cohort. Altered function has now been demonstrated in various sensory domains, most notably olfaction, taste, and vision. Touch and hearing appear not to be influenced by PD, although more data are needed to adequately power these elements of the study. The early sensory alterations found in this study appear to be uninfluenced by LDOPA repletion.