Purification of Erythropoietin by Ion-Exchange Chromatography.

摘要

A method is given for the purification of erythropoietin from the filtrate of acidified, boiled plasma prepared from phenylhydrazine anemic rabbits utilizing, DEAE-cellulose ion-exchange columns. The active erythropoietic factor thus prepared has been partially characterized and shown to be an acidic glycoprotein of low molecular weight.