The approach outlined consisted of three phases:(a) synthesis of analogs of" naturally occurring physiologically active indoles, (b) synthesis of other heterocyclic nitrogen compounds that are related to those possessing physiological activities of interest to the ACRDL, and (c) attempts to improve upon i he methods of synthesis of compounds found to possess activities of interest.nInitial synthetic work is directed toward synthesis of analogs of psilocin (3-dimethy 1aminoethy1-4-hydroxyindole) . These compounds are being evaluated for physiological activity as hallucinogens by the ACRDL.
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